2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid

2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid - Names and Identifiers

Name	2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid
Synonyms	Ambrisentan PI-2 Ambrisentan Intermediate 2-Hydroxy-3-methoxy-3,3-diphenylpropanoicaci 2-HYDROXY-3-METHOXY-3,3-DIPHENYLPROPANOIC ACID 2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid 2-hydroxy-3-methoxy-3,3-diphenyl-propionic acid Benzenepropanoic acid, α-hydroxy-β-methoxy-β-phenyl- alpha-Hydroxy-beta-methoxy-beta-phenylbenzenepropanoic acid Benzenepropanoic acid, alpha-hydroxy-beta-methoxy-beta-phenyl-
CAS	178306-51-9
EINECS	605-820-8
InChI	InChI=1/C16H16O4/c1-20-16(14(17)15(18)19,12-8-4-2-5-9-12)13-10-6-3-7-11-13/h2-11,14,17H,1H3,(H,18,19)

2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid - Physico-chemical Properties

Molecular Formula	C16H16O4
Molar Mass	272.3
Density	1.248
Boling Point	430℃
Flash Point	158℃
Vapor Presure	0mmHg at 25°C
pKa	3.24±0.28(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Sensitive	IRRITANT
Refractive Index	1.592
MDL	MFCD13152279

2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid - Risk and Safety

Hazard Class

IRRITANT

2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid - Introduction

2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid(2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid) is an organic compound. The following is a description of some of the properties, uses, preparation methods and safety information of the compound:

Nature:
-Appearance: White crystal or crystalline powder
-Molecular formula: C18H16O4
-Molecular weight: 296.32g/mol
-Melting point: 110-113 ° C

Use:
2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid is a very important pharmaceutical intermediate, often used in the preparation of other organic compounds. It has a wide range of applications in the pharmaceutical field, usually for the synthesis of anti-inflammatory drugs and analgesic drugs. In addition, it can also be used as a catalyst or ligand in organic synthesis reactions.

Method:
2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid has many preparation methods. One of the commonly used methods includes oxidation reaction and benzylation reaction after treatment of methyl ketone benzene, and finally the target product is obtained. The specific preparation method may vary depending on the reaction conditions and the desired purity.

Safety Information:
2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid is a relatively safe compound under correct handling and storage conditions. However, as an organic compound, it may cause certain harm to human body and environment. Wear appropriate protective equipment, such as lab gloves and glasses, to avoid contact with skin and eyes. At the same time, it should be kept away from fire sources and flammable substances to avoid contact with oxygen.

Please note that the information provided above is for reference only. Relevant literature and safety data sheets should be carefully read before use. In the use of chemical substances, should follow the correct operating procedures and safety measures.

Last Update：2024-04-09 21:11:58